Table 2.
Patients with aMCI and MCI PD
| Healthy controls | aMCI | MCI PD | |||||||
|---|---|---|---|---|---|---|---|---|---|
| (females: 10, males: 10) |
(females: 14, males: 11) |
(females : 16, males : 13) |
|||||||
| mean | median | SD | mean | median | SD | mean | median | SD | |
| Age, years | 68.8 | 74.0 | 14.9 | 69.7 | 71.0 | 9.1 | 71.1 | 73.0 | 7.9 |
| Education, years | 13.3 | 12.0 | 2.5 | 12.9 | 12.5 | 2.8 | 12.4 | 12.0 | 2.3 |
| MMSE | 28.8 | 29.0 | 0.5 | 26.2 | 26.0 | 2.5 | 27.8 | 28.0 | 1.4 |
| Tau protein, pg/ml | – | – | – | 459 | 355 | 356 | – | – | – |
| Beta-amyloid, pg/ml | – | – | – | 658.2 | 637 | 302.7 | – | – | – |
| Hoehn and Yahr Scale | – | – | – | – | – | – | 3.4 | 3.5 | 0.5 |
| Beck Depression Inventory | 5.4 | 5.3 | 1.3 | 10.1 | 9.0 | 6.8 | 9.6 | 8.0 | 6.8 |
| Rey Verbal Comprehension | 1.00 | 1.00 | 2.65 | 3.00 | 1.50 | 2.52 | 2.00 | 1.94 | |
| Mehrfachwahl-Wortschatz-Intelligenztest | 31.8 | 31.5 | 2.1 | 28.0 | 30.0 | 4.9 | 27.6 | 27.0 | 5.2 |
| Boston Naming Test1 | 15.0 | 15.0 | 0.0 | 13.9 | 14.0 | 3.3 | 14.0 | 15.0 | 1.4 |
| Semantic fluency1 | 18.8 | 19.5 | 6.7 | 13.2 | 13.0 | 3.2 | 15.0 | 16.0 | 5.7 |
| LPS subtest 6 (phonological fluency) | 27.5 | 26.5 | 6.2 | 22.0 | 22.0 | 8.9 | 21.7 | 21.0 | 8.7 |
| ZVT, s* | 34.3 | 36.0 | 10.8 | 45.9 | 34.0 | 25.7 | 83.9 | 70.0 | 53.5 |
| Digit Span forward* | 9.3 | 9.5 | 1.0 | 6.4 | 6.0 | 1.9 | 8.1 | 8.0 | 2.3 |
| Digit Span backward | 8.0 | 8.0 | 1.6 | 5.6 | 5.0 | 4.6 | 5.4 | 5.0 | 1.8 |
| Copying1, * | 10.3 | 11.0 | 1.5 | 9.4 | 10.0 | 1.2 | 9.0 | 9.0 | 2.0 |
| Word list learning1 | 22.3 | 21.0 | 4.0 | 13.6 | 15.0 | 3.8 | 16.6 | 17.0 | 5.0 |
| Word list delayed recall1, * | 6.3 | 5.5 | 1.9 | 3.5 | 3.0 | 2.0 | 5.5 | 5.0 | 1.4 |
| Word list intrusions1 | 0.8 | 1.0 | 0.5 | 0.9 | 0.0 | 1.2 | 0.9 | 1.0 | 1.7 |
| Word list savings1, * | 73.8 | 74.5 | 16.8 | 63.6 | 67.0 | 32.9 | 82.8 | 84.0 | 16.2 |
| Visuoconstructive delayed recall1 | 9.5 | 9.5 | 1.7 | 5.1 | 5.0 | 2.7 | 6.8 | 7.0 | 3.2 |
| Visuoconstructive savings1 | 93.3 | 100.0 | 13.5 | 53.6 | 56.0 | 27.4 | 73.6 | 75.0 | 29.5 |
| Word list discriminability1 | 97.5 | 100.0 | 5.0 | 88.6 | 90.0 | 9.6 | 94.8 | 95.0 | 7.0 |
| Word list recognition: correct hits1 | 0.5 | 0.0 | 1.0 | 1.4 | 1.0 | 1.4 | 0.9 | 0.0 | 1.4 |
| Word list recognition: correct rejections1 | 0.5 | 0.0 | 1.0 | 0.8 | 0.0 | 1.0 | 0.2 | 0.0 | 0.5 |
| Visual recognition task: omissions | 0.5 | 0.5 | 0.6 | 2.0 | 1.0 | 1.7 | 1.5 | 1.0 | 1.7 |
| Visual recognition task: commissions* | 0.5 | 0.5 | 0.6 | 2.8 | 1.0 | 3.2 | 0.8 | 0.0 | 1.0 |
1
CERAD-NP battery.
*
p < 0.05 comparing aMCI with MCI PD patients.