Fig. 2.

Gastrulation defect phenotypes associated with ciliary dysfunction. Embryos with disrupted ciliary gene expression (by morpholino suppression in this example) exhibit gastrulation defects that manifest at somitic stages as shortened body axes, widened and kinked notochords, and widened and thinned somites. Embryos can be categorized, based on the extent and severity of the phenotypes, into Class I (moderately affected) and Class II (severely affected).