Table 2.

Multivariable competing risk analysis for the risk of SCD and incident CHD associated with different demographic and clinical variables

Characteristic	Definite SCD HR (95% CI)*	Incident CHD HR (95% CI)*	p Value†
ARIC study (vs CHS)	1.09 (0.62 to 1.89)	0.84 (0.70 to 1.00)	0.3889
Age (per decade)‡	2.61 (1.71 to 3.97)	1.75 (1.53 to 2.01)	0.0788
Male sex (vs female)	2.42 (1.77 to 3.30)	2.03 (1.84 to 2.24)	0.2930
Black race/ethnicity (vs non-black)	1.81 (1.31 to 2.49)	0.76 (0.67 to 0.86)	<0.0001
BMI			0.0220
BMI (kg/m2)	0.49 (0.23 to 1.03)	1.14 (0.79 to 1.63)
BMI2 (kg/m2)	1.07 (1.01 to 1.13)	0.99 (0.96 to 1.02)
Smoking status (vs current)			0.7477
Never	0.59 (0.40 to 0.86)	0.69 (0.61 to 0.78)
Former	0.70 (0.48 to 1.01)	0.76 (0.68 to 0.85)
Diabetes	2.54 (1.84 to 3.50)	2.08 (1.86 to 2.32)	0.2470
Hypertension	2.17 (1.60 to 2.93)	1.57 (1.43 to 1.72)	0.0460
LDL-cholesterol (mg/dl)	1.12 (0.98 to 1.29)	1.27 (1.22 to 1.33)	0.0869
HDL-cholesterol (mg/dl)	0.92 (0.76 to 1.11)	0.80 (0.75 to 0.86)	0.1880
Triglycerides (mg/dl)	0.99 (0.85 to 1.15)	1.06 (1.02 to 1.11)	0.3517
White blood cell count (×103/μl)	1.27 (1.11 to 1.46)	1.15 (1.11 to 1.21)	0.1759

^*Unless described otherwise, HRs for continuous variables are per 1 SD increase and for the abnormal value for the categorical variables adjusted for the rest of the variables in the table.

^†Assessing equivalence of HRs for the two end points.

^‡For age, timescale is time since study entry; for all other variables, timescale is age.

BMI, body mass index; CHD, coronary heart disease; LDL, low-density lipoprotein; HDL, high-density lipoprotein; SCD, sudden cardiac death.