. Author manuscript; available in PMC: 2013 Apr 29.

Published in final edited form as: Res Autism Spectr Disord. 2013 Jan 1;7(1):82–92. doi: 10.1016/j.rasd.2012.07.005

Table 5.

Analysis 1: volumetric comparisons between school age children with Autistic Disorder (n = 31) and typically developing children controlling for IQ status (n = 30).

	Total raw regional volume controlled for total brain volume
	Group effect coefficient	Group effect p value
Cortical areas
Supplemental motor cortex	2.102	0.352
Fronto-orbital cortex	−6.366	0.101
DLPFC	−8.785	0.320
Anterior cingulate gyrus	−0.468	0.874
Subcortical areas
Caudate	−3.150	0.026
Putamen	−0.328	0.739
Globus pallidus	−0.925	0.103
Diencephalon	0.548	0.735

Anatomical unit volumes were compared between groups by a multiple regression linear model.

Group effect coefficient indicates the expected change in volume (in cubic centimeters, cm³) for an autistic subject relative to a control for a given IQ status and total brain volume. A positive coefficient means a larger volume in AD subjects and a negative mean a larger volume in controls.

DLPFC, dorsolateral prefrontal cortex; diencephalon, thalamus + hypothalamus.