TABLE 1:

Summary of the DNA, bilobe, and FAZ states of synchronized cells upon treatment with 3MB-PP1 at different cell cycle stages.

	Cells harvested at t = 7.5 h
3MB-PP1 added at t (h)	Abnormal DNA states?	Bilobe duplication?	FAZ duplication?
0	Yes	Impaired	Impaired
3.5	No	Normal	Partial
5.5	No	Normal	Normal

Cells synchronized by elutriation were treated with 3MB-PP1 after 0, 3.5, or 5 h in culture. The cells were then fixed and stained with DAPI to evaluate their DNA state, along with antibodies against the FAZ or bilobe to assess the status of these structures.