Table 4.
Risk factors of adverse events during IHT
|
Qualitative data |
Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
|
Treatments before transport |
|
|
|
|
| Dialysis |
0.76 (0.44-1.32) |
NS |
|
|
| Sedation |
2.02 (1.22-3.34) |
0.008 |
1.85 (1.1-3.11) |
0.021 |
| Neuromuscular blockers use |
1.55 (0.69-3.45) |
NS |
|
|
| Norepinephrine before transport |
1.61 (0.84-3.06) |
NS |
|
|
| Dobutamine before transport |
1.21 (0.58-2.54) |
NS |
|
|
|
Ventilatory mode before IHT |
|
|
|
|
| VAC |
0.9 (0.48-1.69) |
NS |
|
|
| BIPAP |
0.94 (0.36-2.47) |
NS |
|
|
| PSV |
1.42 (0.65-3.11) |
NS |
|
|
| FiO2 before IHT >60% |
1.51 (0.81-2.83) |
NS |
|
|
| PEEP before IHT >6 cmH2O |
2.27 (1.34-3.85) |
0.003 |
2.28 (1.32-3.95) |
0.003 |
|
Transport |
|
|
|
|
| More than four infusion pumps for transport |
3.4 (0.88-13.03) |
0.071 |
|
NS |
| Ventilatory mode change for transport |
1.3 (0.64-2.65) |
NS |
|
|
| Change of PEEP for transport |
0.84 (0.05-13.64) |
NS |
|
|
| Treatment modification for transport |
2.22 (1.23-4.01) |
0.011 |
|
NS |
| Sedation for transport |
1.77 (0.88-3.55) |
NS |
|
|
| Neuromuscular blocker use for transport |
1.2 (0.44-3.29) |
NS |
|
|
| Fluid challenge for transport |
6.36 (1.37-29.64) |
0.014 |
6.48 (1.32-31.69) |
0.021 |
|
Quantitative data |
|
|
Univariate |
Multivariate |
| |
Without AE |
With AE |
analysis |
analysis |
|
Patient data (Med (25th ,75th )) |
|
|
|
|
| Age (yr) |
61 (44–74) |
58 (50.5-68) |
NS |
|
| SAPS II |
48 (34–61) |
48 (34–64) |
NS |
|
|
Transport's data (Med (25th ,75th )) |
|
|
|
|
| SOFA the day of transport |
5 [3-7] |
5 [3-8] |
NS |
|
| MV duration before transport (days) |
4 [2–11.25] |
4 [2–10.75] |
NS |
|
| No. of infusion pumps during transport | 2 [1-3] | 3 [2,3] | p = 0.015 | NS |
VAC = volume assist–control; BIPAP = bi-level positive airway pressure; PSV = pressure support ventilation; FiO2 = fraction of inspired oxygen; PEEP = positive end-expiratory pressure; SOFA = Sepsis-related Organ Failure Assessment; SAPS II = Simplified Acute Physiology Score; MV = mechanical ventilation; OR = odds ratio; CI = confidence interval.