Table 5.
Risk factors of patient-related adverse events during IHT
|
Qualitative data |
Univariate analysis |
|||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
|
Treatments before transport |
|
|
|
|
| Dialysis |
0.84 (0.45-1.58) |
NS |
|
|
| Sedation |
1.48 (0.83-2.61) |
NS |
|
|
| Neuromuscular blockers use |
0.78 (0.3-2.02) |
NS |
|
|
| Norepinephrine before transport |
1.71 (0.86-3.39) |
NS |
|
|
| Dobutamine before transport |
1.11 (0.49-2.53) |
NS |
|
|
|
Ventilatory mode before IHT |
|
|
|
|
| VAC |
1.09 (0.53-2.24) |
NS |
|
|
| BIPAP |
1.44 (0.52-3.99) |
NS |
|
|
| PSV |
0.74 (0.29-1.91) |
NS |
|
|
| FiO2 before IHT > 60% |
1.52 (0.77-2.99) |
NS |
|
|
| PEEP before IHT > 6 cmH2O |
2.16 (1.22-3.81) |
0.01 |
2.11 (1.17-3.8) |
0.01 |
|
Transport |
|
|
|
|
| More than four infusion pumps for transport |
1.07 (0.28-4.17) |
NS |
|
|
| Ventilatory mode change for transport |
1.14 (0.52-2.51) |
NS |
|
|
| Change of PEEP for transport |
0.76 (0.27-2.13) |
NS |
|
|
| Treatment modification for transport |
2.66 (1.44-4.91) |
0.002 |
2.81 (1.5-5.3) |
0.001 |
| Sedation for transport |
3.05 (1.5-6.21) |
0.003 |
|
NS |
| Neuromuscular blocker use for transport |
0.93 (0.29-2.98) |
NS |
|
|
| Fluid challenge for transport |
2.97 (0.92-9.54) |
0.087 |
|
NS |
|
Quantitative data |
Without AE |
With AE |
Univariate analysis ( p ) |
|
|
Patient data (Med (25th ,75th)) |
|
|
|
|
| Age (yr) |
57.5 [46–71.25] |
59.5 [50.75-69.5] |
NS |
|
| SAPS II |
47 [34–61.5] |
49 [34–64] |
NS |
|
|
Transport data (average ± SD) |
|
|
|
|
| SOFA the day of transport |
5 [2-8] |
5 [3–8.75] |
NS |
|
| MV duration before transport (days) |
4.5 [2–12.25] |
3.5 [2–9.75] |
NS |
|
| No. of infusion pumps during transport | 2 [1-3] | 2 [2,3] | NS | |
VAC = volume assist–control; BIPAP = bi-level positive airway pressure; PSV = pressure support ventilation; FiO2 = fraction of inspired oxygen; PEEP = positive end-expiratory pressure; SOFA = Sepsis-related Organ Failure Assessment; SAPS II = Simplified Acute Physiology Score; MV = mechanical ventilation; SD = standard deviation; OR = odds ratio; CI = confidence interval; NS = not significant.