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. Author manuscript; available in PMC: 2013 Apr 29.
Published in final edited form as: Autoimmunity. 2012 Apr 19;45(5):388–399. doi: 10.3109/08916934.2012.665523

Figure 2.

Figure 2

CD4+ cells produce IL-10 in the CNS during EAE. EAE was induced in IL-10–IRES–eGFP reporter mice by adoptive transfer of 1 × 106 encephalitogenic T cells per mouse. Clinical signs of EAE were scored daily. At onset (day 7), peak (day 14) and resolution (day 22) of EAE disease the percentages of CD11b–-gated CNS infiltrating CD4+ and CD19+ that were EGFP– and EGFP+ were determined by flow cytometry and the percentage of each population is indicated on the graphs. Representative data from one of three mice at each time point is shown.