. Author manuscript; available in PMC: 2013 Apr 29.

Published in final edited form as: Autoimmunity. 2012 Apr 19;45(5):388–399. doi: 10.3109/08916934.2012.665523

Table I.

Common models of rat and mouse EAE

Species	Strain	Antigen	EAE induction	Disease course	B cell role	References^a
Rat	Lewis	MBP protein	Active immunization	Acute Monophasic Recovery	EAE onset, Antibody?	[9,10,14]
Mouse	C57BL/6	MOG_35-55 peptide	Active immunization	Acute Monophasic Recovery or chronic	Regulatory role in recovery	[28,43,50,61]
Mouse	C57BL/6	rhMOG protein	Active immunization	Acute Monophasic Chronic	EAE onset, Antibody	[41–43,45]
Mouse	SJL/J	PLP_139-151 peptide	Active immunization	Relapsing and remitting Chronic	None known	[49]
Mouse	B10.PL	MBPAc1-11 peptide	Active immunization	Acute Monophasic Recovery	Regulatory role in recovery	[39]
Mouse	B10.PL	MBPAc1-11 peptide	Passive transfer of MBP Ac1-11-specific T cells	Acute Monophasic Recovery	Regulatory role in recovery	[2, 56]

References are selected from this review and are not necessarily the first historical report.