Table 3.
Multivariate analysis of the time of housing renovations and moving-in on CHD occurrence
| Time of moving in renovated house | Interval between renovation and moving-in |
Controls |
Isolated cardiac defects |
P-value | AORa (95%CI) |
|---|---|---|---|---|---|
| N = 408 (%) | N = 281 (%) | ||||
| No renovation |
|
331 (81.1) |
201 (71.5) |
|
Reference |
| 7-12 months before pregnancy |
<1 months |
3 (0.7) |
3 (1.1) |
0.664 |
1.50 (0.24, 9.37) |
| 1–3 months |
3 (0.7) |
1 (0.4) |
0.992 |
0.99 (0.09, 11.04) |
|
| ≥4 months |
2 (0.5) |
3 (1.1) |
0.256 |
3.01 (0.45, 20.15) |
|
| 4-6 months before pregnancy |
<1 months |
3 (0.7) |
6 (2.1) |
0.108 |
3.59 (0.76, 17.04) |
| 1–3 months |
5 (1.2) |
4 (1.4) |
0.727 |
1.33 (0.27, 6.62) |
|
| ≥4 months |
4 (1.0) |
3 (1.1) |
0.659 |
1.42 (0.30, 6.85) |
|
| 3 months before pregnancy |
<1 months |
13 (3.2) |
18 (6.4) |
0.042 |
2.38* (1.03, 5.48) |
| 1–3 months |
8 (2.0) |
8 (2.8) |
0.346 |
1.70 (0.56, 5.16) |
|
| ≥4 months |
12 (2.9) |
3 (1.1) |
0.222 |
0.42 (0.10, 1.69) |
|
| first trimester |
<1 months |
8 (2.0) |
24 (8.5) |
0.003 |
4.00** (1.62, 9.86) |
| 1–3 months |
5 (1.0) |
5 (1.8) |
0.532 |
1.54 (0.40, 5.94) |
|
| ≥4 months |
9 (2.2) |
2 (0.7) |
0.506 |
0.58 (0.12, 2.97) |
|
| Missing | 2 (0.5) | 0 (0.0) |
a Variables entered were maternal age, maternal education level, place of residence (category), folate intake, ETS, factory or landfill nearby, air ventilation and hospital distribution (category).
Significant differences between the mothers of case and control group were indicated as follows: * (p < 0.05), ** (p < 0.01) (tested two-tailed).