Figure 2. RLR activation by dsRNA/LyoVec evokes BSMC mRNA expression and protein production of IFN-β and IFN-λ₁.

IFN-β and IFN-λ₁ mRNA expression was increased by dsRNA/LyoVec (dsRNA/LV) after 3 h (A, D) and 24 h (B, E) and so was secretion of IFN-β and IFN-λ₁ after 24 h (C, F). Data are presented as mean with SEM and n = 8–10 (BSMCs from three individual donors). *p≤0.05, **p≤0.01 and ***p≤0.001 compared to non-stimulated cells (control).