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. 2013 Apr 29;8(4):e62718. doi: 10.1371/journal.pone.0062718

Figure 4. dsRNA increase expression of TNF-α and CXCL8 in BSMCs.

Figure 4

BSMCs were stimulated with dsRNA for 3 h (A, C) and 24 h (B, D). mRNA expression of TNF-α (A-B) and CXCL8 (C-D) was increased concentration-dependently. CXCL8 protein was secreted into cell supernatants (E) and partly reduced by chloroquine (F). Data are presented as mean with SEM and n = 8–10 (BSMCs from three individual donors). *p≤0.05, **p≤0.01 and ***p≤0.001 compared to non-stimulated cells (control). ###p≤0.001 compared to 10 µg/ml dsRNA.