Table 4.
Comparison of the previous reports analyzing the perioperative change of serum CEA levels in patients with pathological stage-I NSCLC
| Author | Okada [4] | Matsuguma [11] | Wang [15] | Present study | |||
|---|---|---|---|---|---|---|---|
| Year |
2004 |
2008 |
2010 |
2013 |
|||
| CEA measurement period |
Before surgery |
Within 1 M |
Within 1 M |
Within 2 W |
Within 1 M |
||
| After surgery |
Within 1 M |
Within 1–3 M |
Within 1–3 M |
Within 2 M |
|||
| Cut-off point (ng/mL) |
5.0 |
5.0 |
6.0 |
5.0 |
|||
| Total number |
722 a |
455 |
257 |
263 |
|||
| NN group |
(5-ys) |
472 (84.2%) |
323 (85.9%) |
173 (71.1%) |
198 (95.5%) |
||
| HN group |
154 (74.2%) |
112 (56.2%) |
56 (54.6%) |
44 (85.5%) b |
|||
| HH group |
96 (48.6%) |
20 (43.1%) |
28 (36.0%) |
21 (59.3%) |
|||
| Independent prognostic factor | N/A | Age |
Age |
Tumor diameter |
|||
| Histology |
HH group |
VPI |
|||||
| VPI |
|
HH group |
|||||
| HN/HH group | |||||||
CEA, Carcinoembryonal antigen; NSCLC, Non-small cell lung cancer; M, Month; W, Week; N/A, Not analyzed; VPI, Visceral pleural invasion.
a including incomplete resections.
b 4-ys.