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. 2013 Apr 29;8(4):e62283. doi: 10.1371/journal.pone.0062283

Figure 7. The 6BPGC hairpin serves as a +1 PRF stimulator when placed upstream of a +1 shifty site in yeast.

Figure 7

(A) Schematic drawing for the flanking sequences surrounding the 6BPGC hairpin in yeast +1 frameshifting reporter constructs. Construct with a disrupted attenuator hairpin (5′-WT) was designated by Δ and the 5′-flanking sequence of 6BPGC hairpin was designed to prevent forming base-pairs with E site sequences. (B) Fold change of the AGG- and 6BPGC-dependent +1 frameshifting activity in yeast using the activity of the CGG.E.CGC construct as 1. Error bars, s.d.; n = 6.