Table 1. SPECTRUM screening summary in 384-well plates.

			Number of Hits
	S/B	Z-factor	>60%	>50%	>40%
10 µM	11.47±0.56	0.58±0.06	1	1	6
20 µM	23.04±1.38	0.71±0.03	1	3	28
40 µM	9.22±0.97	0.54±0.06	0	4	26

S/B = signal to background. Hits are expressed as % inhibition. S/B and Z-factors were calculated by averaging the S/B and Z-factors in seven plates per concentration. n = 32 wells per treatment.