Table 2. LOPAC screening summary in 1536-well plates.

			Number of Hits
	S/B	Z-factor	>60%	>50%	>40%
5 µM (0.25% DMSO)
Replicate 1	18.7	0.70	5	8	9
Replicate 2	21.1	0.72	3	6	10
Replicate 3	20.3	0.71	6	6	7
10 µM (0.25% DMSO)
Replicate 1	19.0	0.68	4	6	9
Replicate 2	21.0	0.71	4	7	11
Replicate 3	19.0	0.71	6	9	9
20 µM (0.25% DMSO)
Replicate 1	20.0	0.69	4	9	13
Replicate 2	20.3	0.69	6	9	14
Replicate 3	19.5	0.72	7	10	16

S/B = signal to background. Hits are expressed as % inhibition. n = 32 wells per treatment.