Table 1.
Days | C | DC | DFL | DF | CFL | CF |
---|---|---|---|---|---|---|
1a | I.p. injection of saline solution and citrate buffer | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p. injection of saline solution and citrate buffer | I.p. injection of saline solution and citrate buffer |
15a | – | Confirmation of stable hyperglycemia | Confirmation of stable hyperglycemia | Confirmation of stable hyperglycemia | – | – |
16 | Regular feed for 35 days | Regular feed for 35 days | 10 % w/w flaxseed oil feed for 35 days | 10 % w/w fish oil feed for 35 days | 10 % w/w flaxseed oil feed for 35 days | 10 % w/w fish oil feed for 35 days |
51 | Blood samples were collected, animals were killed and liver tissue harvested |
C Control, DC diabetes control, DFL diabetes + flaxseed oil, DF diabetes + fish oil, CFL control + flaxseed oil, CF control + fish oil
aAll the groups were fed regular diet from day 1 until day 15