Table 1.
Experimental design employed in the study
| Days | C | DC | DFL | DF | CFL | CF |
|---|---|---|---|---|---|---|
| 1a | I.p. injection of saline solution and citrate buffer | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p injection of nicotinamide (110 mg/kg) and STZ (65 mg/kg) | I.p. injection of saline solution and citrate buffer | I.p. injection of saline solution and citrate buffer |
| 15a | – | Confirmation of stable hyperglycemia | Confirmation of stable hyperglycemia | Confirmation of stable hyperglycemia | – | – |
| 16 | Regular feed for 35 days | Regular feed for 35 days | 10 % w/w flaxseed oil feed for 35 days | 10 % w/w fish oil feed for 35 days | 10 % w/w flaxseed oil feed for 35 days | 10 % w/w fish oil feed for 35 days |
| 51 | Blood samples were collected, animals were killed and liver tissue harvested | |||||
C Control, DC diabetes control, DFL diabetes + flaxseed oil, DF diabetes + fish oil, CFL control + flaxseed oil, CF control + fish oil
aAll the groups were fed regular diet from day 1 until day 15