Table 1.
Summary of immunohistochemistry
A | B | C | D | E | F | |
---|---|---|---|---|---|---|
HE | dysplasia | dysplasia | dysplasia | dysplasia | dysplasia | SCC |
p16 | mild | mild | moderate | moderate | strong | negative |
p53 | mild | mild | mild | mild | mild | strong |
EGFR | strong | strong | strong | strong | strong | strong |
pEGFR | positive | negative | ||||
pERK | positive | negative |
Specimens obtained from the larynx in 1989 (A), 1994 (B), 2000 (C), 2005 (D), and 2011 (E), and on the tumor tissue obtained from around the tracheotomy aperture in 2011 (F).