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Effects of arsenite on relaxation in aortic rings with intact endothelium. (A) EDHF-type relaxations were <5% of induced tone so that endothelium-dependent relaxation in this vessel can be attributed to NO. (B) Concentration–relaxation curves for CPA and ACh constructed in the absence of L-NAME/indomethacin were unaffected by exposure to 100 μM arsenite for 30 min. n denotes the number of animals studied.
