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. 2013 Apr 30;4:110. doi: 10.3389/fpls.2013.00110

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Copyright © 2013 Azpeitia, Weinstein, Benítez, Mendoza and Alvarez-Buylla.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Figure A3 — Truth tables and equivalent logical statements for global negative, ambiguous, and neutral regulator definitions. (A) Two examples of a negative global regulator. As observed in the first example, the regulator can only be expressed with a NOT logical operator in the logical statement. In the example below, equivalent logical statements where RGEN1 acts as a negative and as an ambiguous regulator can be used. However, we can observe that if RGEN1 is labeled as a negative global regulator, we can always express RGEN1 in a logical statement with a NOT logical operator. (B) An example of ambiguous global regulators. In this example, the regulators can only be expressed as ambiguous regulators using a NOT logical operator in one part of the sentence and omitting the NOT operator in the other part of the sentence. (C) A neutral global regulator. The logical statement can be written without including the neutral global regulator (RGEN2). However, we can use an equivalent logical statement to include RGEN2 as a positive, negative, or neutral regulator. Neutral global regulators can always be removed from the logical statement.