Fig 6.

Effects of deletion of SLR1 on C. albicans virulence in the mouse model of OPC. Immunocompromised mice were infected orally with the wild type (AMC81), the slr1Δ/Δ mutant (AMC82), or the slr1Δ/Δ mutant complemented with SLR1 (AMC104). The oral fungal burden was determined after 5 days of infection for 6 or 7 mice per strain. Each symbol represents the results for an individual mouse, and the horizontal lines indicate the median values. *, P = 0.02 compared to results for the wild-type strain.