Fig 7.

Deletion of SLR1 affects C. albicans virulence, filamentation, and intrakidney localization during disseminated candidiasis. (A) Survival of mice injected intravenously with the wild type (AMC81), the slr1Δ/Δ mutant (AMC82), or the slr1Δ/Δ mutant complemented with SLR1 (AMC104). Each strain was injected into 8 mice, and host survival was monitored over a 3-week period. *, P < 0.0001 versus results for other strains. (B) Histopathology of kidney sections after 4 days of infection with the indicated strains. Sections were stained with periodic acid-Schiff stain. Scale bar = 20 μm.