Fig 4.

C555-91 causes urovirulence in a UTI mouse model without the requirement for AAF/I or AggR expression. Groups of eight mice were inoculated with wild-type (WT) C555-91, the AAF/I mutant, or the AggR mutant. Three days following inoculation, the mice were sacrificed and the bladders (n = 8) and kidneys (n = 16) collected. Urine samples (n = 6 or 7) were collected where possible. Bacteria present in the samples were enumerated as described in Materials and Methods. Values of 0 represent CFU counts below the lower detection limit of 50 CFU/g sample or CFU/ml sample.