Table 4.
Measurement and strain | Value after infectiona |
|||
---|---|---|---|---|
Tg mice |
Non-Tg mice |
|||
7 days | 14 days | 7 days | 14 days | |
Cell body diameter (μm) | ||||
C. neoformans H99 | 11.8 ± 4.2b | 11.4 ± 4.5b | 12.4 ± 3.6b | 15.4 ± 3.5b,c,d |
C. gattii R265 | 10.3 ± 2.8 | 9.8 ± 2.7 | 9.5 ± 2.9 | 12.0 ± 2.8c,d |
Capsule thickness (μm) | ||||
C. neoformans H99 | 5.0 ± 1.9b | 5.6 ± 2.5b | 6.3 ± 1.8b | 8.2 ± 2.0b,c,d |
C. gattii R265 | 4.9 ± 1.4 | 4.7 ± 2.3 | 3.5 ± 1.3 | 6.2 ± 2.0c,d |
Data are means ± standard deviations for 100 randomly selected cells.
P < 0.001 compared to C. gattii R265.
P < 0.001 compared to non-Tg mice at day 7.
P < 0.001 compared to Tg mice at day 14.