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In the open field test, spontaneous activity was evaluated when rats were response to a new environment. Data are expressed as mean ± SD, n = 10 rats per group. (a): **P < 0.01, *P < 0.05, versus the NC group; # P < 0.05, versus the KYDS group. (b): **P < 0.01, *P < 0.05, versus the NC group; # P < 0.05, versus the KYDSA group. (c): **P < 0.01, *P < 0.05, versus the KYDS group or the ASS group.
