Table 1.

HE, PAS and MASSON staining were used to assess the severity of inflammation, epithelial damage, oedema, mucus secretion and collagen deposition in lung tissues.

Group	Inflammatory cells infiltration in the peribronchial and perivascular areas	Oedema	Epithelial damage	Mucus area	Collagen deposition
NC	1.25 (1–3)	0.25 (0-1)	0	4.81 ± 1.91	4.68 ± 0.78
AC	3.12 (2–5)**	2.75 (1–5)**	3.12 (2–5)**	14.66 ± 1.51**	12.69 ± 2.17**
KYDS	2.00 (1–3)	1.75 (1–3)*	1.75 (1–3)*	7.60 ± 0.36	8.67 ± 1.03
ASS	2.05 (1–3)	1.95 (1–5)*	1.06 (1-2)	8.16 ± 0.56	8.32 ± 0.78
KYDSA	4.50 (4-5)∗∗#	2.25 (1–5)**	2.25 (1–5)**	14.75 ± 1.83**	17.68 ± 1.53∗∗#
ASSA	4.01 (4-5)∗∗#	2.58 (1–5)**	3.02 (2–5)**	11.83 ± 1.62**	14.72 ± 1.47**

Lung tissues were stained by HE, PAS and MASSON, and scores mirrored to airway inflammation and airway remodeling were performed blindly by two researchers. The data is shown as average scores ± SD, n = 10. **P < 0.01, *P < 0.05, versus the NC group; ^# P < 0.05, versus the AC group.