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. 2010 Dec 2;376(9757):744–751. doi: 10.1016/S0140-6736(10)62051-X

Table 5.

Response rates after induction therapy (intention-to-treat population)

	Intensive pathway			Non-intensive pathway
	Zoledronic acid (n=555)	Clodronic acid (n=556)	p value	Zoledronic acid (n=426)	Clodronic acid (n=423)	p value
CR, VGPR, or PR	432 (78%)	422 (76%)	0·43	215 (50%)	195 (46%)	0·18
CR or VGPR^*	200 (36%)	193 (35%)	0·63	85 (20%)	60 (14%)	0·018
CR^*	78 (14%)	69 (12%)	0·42	39 (9%)	27 (6%)	0·13

CR=complete response. PR=partial response. VGPR=very good partial response.

^*

Exploratory analyses.