Figure 2.

Schematic overview of the essential intracortical and cortico-cortical interactions between excitatory and inhibitory neuronal populations in the model of Liley et al. (Liley et al., 1999, 2002, 2011; Bojak and Liley, 2005; Frascoli et al., 2011). Following conductance based approaches typically used to model networks of synaptically interacting networks of individual model neurons, excitatory and inhibitory neuronal populations are modeled as single passive resistive-capacitive compartments into which all synaptically induced postsynaptic currents flow. Functionally these populations are equivalent to the excitatory and inhibitory KO sets of Freemans K-set hierarchy (Freeman, 1975). Cortical activity is then described by the mean soma membrane potentials of the spatially distributed excitatory (h_e) and inhibitory (h_i) neuronal populations. The connection with physiological measurement is obtained through h_e, which is assumed to be linearly related to the surface recorded electroencephalogram (Freeman, 1975; Nunez and Srinivasan, 2005). Figure reproduced with permission from Frascoli et al. (2011).