Table 2.
Correlations between cytokine production in H1N1-stimulated PBMC cultures and serum IgG3 levels
| Cytokine in supernatants | IgG3 (t7) Person’s r | p | IgG3 (t28) Person’s r | p |
|---|---|---|---|---|
|
TNF-α |
0.0861 |
0.58 |
0.3545 |
0.0006 |
|
IL-6 |
0.2264 |
0.31 |
0.4556 |
0.0001 |
| IL-10 |
0.3120 |
0.09 |
0.3963 |
0.06 |
| IFN-γ |
0.1623 |
0.96 |
0.1918 |
0.91 |
| IL-4 |
0.0215 |
0.56 |
0.0467 |
0.49 |
| IL-5 |
0.0484 |
0.43 |
0.0513 |
0.40 |
| Blys | −0.1604 | 0.16 | −0.1528 | 0.38 |
PBMC (106 cells/ml) were isolated from the peripheral blood at t0, thawed and cultured with H1N1 (2 μg), for 3 days. At the end of this time, supernatants were collected and analyzed in ELISA for cytokine production. Correlations were calculated by Pearson’s test, using GraphPad Prism 5 software.