Table 1.
Characterization of nanoparticles
|
Group |
Size (nm) |
Polydispersion |
Zeta potential (mV) |
Loading efficiency (%) |
Gene |
Polymer |
|---|---|---|---|---|---|---|
| (n = 3) | (n = 3) | (n = 3) | ||||
| ANP |
72.11 ± 3.44 |
0.164 |
22.54 ± 3.47 |
83.4 ± 2.3 |
TRAIL |
PEI |
| BNP |
71.82 ± 5.18 |
0.156 |
21.58 ± 4.16 |
82.6 ± 1.9 |
Endostatin |
PEI |
| CNP |
83.02 ± 2.35 |
0.178 |
24.65 ± 2.78 |
78.3 ± 3.8 |
TRAIL/endostatin |
PEI |
| DNP |
215.06 ± 3.52 |
0.186 |
−18.25 ± 2.36 |
0 |
None |
TPGS-b-(PCL-ran-PGA) |
| ENP |
236.31 ± 1.44 |
0.201 |
23.65 ± 3.65 |
0 |
None |
PEI/TPGS-b-(PCL-ran-PGA) |
| FNP |
265.48 ± 4.40 |
0.229 |
19.45 ± 1.99 |
67.4 ± 4.3 |
TRAIL |
PEI/TPGS-b-(PCL-ran-PGA) |
| GNP |
245.48 ± 6.42 |
0.215 |
18.45 ± 2.67 |
64.6 ± 3.1 |
Endostatin |
PEI/TPGS-b-(PCL-ran-PGA) |
| HNP | 272.97 ± 4.68 | 0.245 | 16.54 ± 1.06 | 62.5 ± 0.9 | TRAIL/endostatin | PEI/TPGS-b-(PCL-ran-PGA) |