Figure 4. Dendritic cell frequencies and activation in the spleen and mesenteric lymph nodes.

Dendritic cells were gated based on the expression of CD11c and MHC II. Within the dendritic cell population the frequency of CD103⁺ or CD80⁺ was determined. CD103⁺ dendritic cell frequencies in the spleen (N = 6) (A) and MLN (B) following oral treatment with medium (white bars), WT (grey bars), or dltX-D (black bars). CD80⁺ DC frequencies in the MLN (N = 6) (C) and spleen (D). Results are depicted as the mean ± standard error of the mean (SEM). Statistical significance was calculated using the Students t- test. *represents P-values <0.05.