Figure 2. Reticulocyte counts and OFF-score trends during the two race events.

The figure shows the trends of Ret relative count (Ret%), Ret absolute number (Ret#) and OFF-score during the 2010 (black • and solid line, n = 144) and the 2012 (grey ▪ and dotted line; n = 109) races. The thinner lines (solid for 2010 and dotted for 2012) represent the 5^th–95^th percentile for Ret% and Ret#, while for the OFF-score they represent the 95% confidence intervals. The asterisks (*) indicate significant differences between different time-points in the same race (*: p<0.05; **: p<0.01; ***: p<0.001). # indicate that the value of the time-point in the 2012 race is significantly different from that recorded in the 2010 event (##: p<0.01, ###: p<0.001).