Table 1. Baseline characteristics, overall, and separately for subjects of Caucasian and Black ethnicity.
| Variable | Overall§ (n = 557) | Caucasian ethnicity (n = 381) | Black ethnicity (n = 156) |
| Gender, male | 427 (77) | 353 (93) | 61 (39) |
| Age, years | 44 (9) | 45 (10) | 44 (8) |
| Nadir CD4+, cells/µL | 177 (117) | 189 (117) | 147 (109) |
| Baseline CD4+, cells/µL | 553 (217) | 569 (219) | 512 (205) |
| Years undetectable HIV RNA | 4 (3) | 4 (3) | 4 (3) |
| Years education | 15 (4) | 15 (4) | 15 (4) |
| Years on cART | 5 (3) | 5 (3) | 5 (3) |
| on NNRTI | 296 (53) | 187 (49) | 102 (65) |
| Efavirenz | |||
| never on | 217 (39) | 147 (39) | 59 (38) |
| not currently on but previously | 125 (22) | 93 (24) | 27 (17) |
| currently on | 215 (39) | 141 (37) | 70 (45) |
| efavirenz ever stopped due to CNS problems† | 67 (12) | 55 (14) | 11 (7) |
| baseline CPE score | 7 (1) | 7 (1) | 8 (1) |
| Smoker | |||
| never | 261 (47) | 143 (38) | 113 (72) |
| current | 157 (28) | 135 (35) | 17 (11) |
| ex-smoker | 139 (25) | 103 (27) | 26 (17) |
| CV risk | |||
| <10% | 341 (61) | 199 (52) | 127 (82) |
| 10–20% | 187 (34) | 158 (41) | 26 (17) |
| >20–30% | 28 (5) | 24 (6) | 2 (1) |
| Hepatitis C antibody positive | 21 (4) | 18 (5) | 2 (1) |
| Baseline haemoglobin, g/dL | 14 (1) | 15 (1) | 13 (1) |
| Anxiety/Depression | |||
| not anxious/depressed | 369 (67) | 249 (66) | 106 (70) |
| moderately anxious/depressed | 173 (31) | 121 (32) | 46 (30) |
| extremely anxious/depressed | 9 (2) | 9 (2) | 0 |
Table 1 legend: §only patients with complete neurocognitive data (including patients of ethnicity other than Caucasian or Black, n = 20); †5/67 (all Caucasian) were back on efavirenz at baseline; cART = combination antiretroviral therapy, CPE = Clinical Penetration Effectiveness, CV = cardiovascular, NNRTI = non-nucleoside reverse-transcriptase inhibitor; Data are number (%) or mean (standard deviation).