Table 3. Factors associated with incidence of drug resistance in 2010.
| Variable | Number | HIVDR | Person year | Incidence/100 personyear | HR (95% CI) | P-value | Adjusted HR(95% CI) | P-value |
| Total | 1893 | 64 | 1837.3 | 3.5 | ||||
| Sex | ||||||||
| Male | 1166 | 47 | 1128.3 | 4.2 | ||||
| Female | 727 | 17 | 709.0 | 2.4 | 0.6(0.3,1.0) | 0.07 | ||
| Age | ||||||||
| ≤30 | 376 | 12 | 366.1 | 3.3 | ||||
| 31–40 | 862 | 33 | 842.2 | 3.9 | 1.3(0.6,2.4) | 0.50 | ||
| 41–50 | 422 | 15 | 406.0 | 3.7 | 1.2(0.5,2.5) | 0.70 | ||
| >50 | 233 | 4 | 223.1 | 1.8 | 0.7(0.2,2.1) | 0.49 | ||
| Married | ||||||||
| Yes | 1309 | 43 | 1276.0 | 3.4 | ||||
| No | 584 | 21 | 561.4 | 3.7 | 1.1(0.7,1.9) | 0.65 | ||
| Education | ||||||||
| Junior high school or more | 1172 | 36 | 1140.1 | 3.2 | ||||
| Primary school or less | 721 | 28 | 697.3 | 4.0 | 1.2(0.7,1.9) | 0.58 | ||
| Occupation | ||||||||
| Farmer | 987 | 32 | 947.8 | 3.4 | ||||
| Other | 906 | 32 | 889.6 | 3.6 | 1.3(0.8,2.2) | 0.27 | ||
| Monthly income per person within the family (RMB) | ||||||||
| <400 | 875 | 39 | 861.5 | 4.5 | ||||
| ≥400 | 1018 | 25 | 975.8 | 2.6 | 0.8(0.5,1.3) | 0.29 | ||
| Spouse receives ART | ||||||||
| No | 1452 | 53 | 1405.5 | 3.8 | ||||
| Yes | 441 | 11 | 431.8 | 2.5 | 0.7(0.4,1.3) | 0.28 | ||
| HIV transmission route | ||||||||
| Sexual intercourse | 1084 | 34 | 1056.7 | 3.2 | ||||
| Drug injection | 393 | 17 | 387.9 | 4.4 | 1.1(0.6,2.0) | 0.73 | ||
| Blood donation or transfusion | 301 | 10 | 281.2 | 3.6 | 1.3(0.7,2.7) | 0.42 | ||
| Other | 115 | 3 | 111.5 | 2.7 | 0.9(0.3,3.1) | 0.91 | ||
| Initial ART regimen | ||||||||
| AZT/D4T +3TC+EFV | 376 | 10 | 362.0 | 2.8 | ||||
| AZT/D4T+DDI+NVP | 85 | 6 | 79.2 | 7.6 | 4.1(1.5,11.3) | 0.01 | 4.5(1.6,12.6) | <0.01 |
| AZT/D4T +3TC+NVP | 1375 | 48 | 1343.8 | 3.6 | 1.1(0.5,2.1) | 0.9 | 0.8(0.4,1.7) | 0.58 |
| Other | 57 | 0 | 52.4 | 0.0 | – | – | – | – |
| Baseline ART regimen(2009) | ||||||||
| AZT/D4T +3TC+EFV | 569 | 19 | 549.9 | 3.5 | ||||
| AZT/D4T+DDI+NVP | 33 | 2 | 32.3 | 6.2 | ||||
| AZT/D4T +3TC+NVP | 1187 | 39 | 1160.9 | 3.4 | ||||
| Second-line regimen | 49 | 1 | 43.6 | 2.3 | ||||
| Other | 55 | 3 | 50.7 | 5.9 | ||||
| Duration of ART (year) | ||||||||
| 0–12 | 694 | 27 | 660.8 | 4.1 | ||||
| 13–24 | 477 | 18 | 467.0 | 3.9 | 0.7(0.4,1.3) | 0.29 | ||
| 25–36 | 354 | 8 | 349.6 | 2.3 | 0.4(0.2,0.8) | 0.01 | ||
| >37 | 368 | 11 | 360.0 | 3.1 | 0.5(0.2,1.0) | 0.04 | ||
| Missed doses in the past month | ||||||||
| No | 1838 | 59 | 1786.2 | 3.3 | ||||
| Yes | 92 | 5 | 85.7 | 5.8 | 2.3(0.9,5.9) | 0.07 | ||
| Taking drugs on time | ||||||||
| <90% | 73 | 5 | 70.9 | 7.1 | ||||
| ≥90% | 1820 | 59 | 1766.4 | 3.3 | 0.5(0.2,1.2) | 0.12 | ||
| ART drug distribution institute | ||||||||
| County hospital or CDC | 1525 | 44 | 1483.6 | 3.0 | ||||
| Village clinic or township hospital | 368 | 20 | 353.7 | 5.7 | 1.6(0.9,2.7) | 0.10 | 1.8(1.0,3.3) | <0.05 |
| Interval of refilling drug in the past month | ||||||||
| Less than one month | 1081 | 36 | 1026.1 | 3.5 | ||||
| More than one month | 812 | 28 | 811.2 | 3.5 | 0.8(0.5,1.3) | 0.37 | ||
| CD4 cell counts at baseline(2009) | ||||||||
| ≥350 | 797 | 18 | 785.5 | 2.3 | ||||
| 200?350 | 647 | 23 | 626.7 | 3.7 | 2.1(1.1,3.9) | 0.02 | 2.0(1.1,3.7) | 0.03 |
| <200 | 449 | 23 | 425.1 | 5.4 | 4.1(2.1,7.8) | <0.01 | 3.5(1.8,6.9) | <0.01 |
| Viral Load at baseline(2009) | ||||||||
| VL<1000 | 1773 | 45 | 1724.2 | 2.6 | ||||
| VL≥1000 | 120 | 19 | 113.1 | 16.8 | 9.5(5.5,16.5) | <0.01 | 7.1(4.0,12.7) | <0.01 |