Figure 5. Results of the stochastic model.

(A) Example time-series of cell growth rate for a cell with fast (green), slow (blue) and very slow (red) response. (B) Fluorescence time-series for the cells shown in (A). Inset: The same data on a logarithmic scale, showing that cells with higher expression levels at the time of shift of medium tend to be induced more rapidly. (C) Histograms of growth (red) and fluorescence (green) recovery times, ΔTμ₂ and ΔT_F. In panels (C) and (D), cells at ΔTμ₂ = 0 showed a decrease in growth rate of less than 20%. (D) Lac expression of each lineage at t_shift plotted against growth recovery time. Cells which did not reach the induction threshold in the time of the simulations are placed at ΔTμ₂ = 500 min. Cells with initial concentrations above ∼10 nM typically have a rapid recovery of growth rate. Note that the plot range does not represent the full range of initial expression levels.