Table 2. Age-associated genes specific to mouse SNpc.
| Gene symbol | Entrez gene description | Fold change* | pFDR |
| 1600021P15Rik | RIKEN cDNA 1600021P15 gene | −1.40 | 0.041 |
| AA467197 | expressed sequence AA467197 | 1.60 | 0.048 |
| Ang | angiogenin, ribonuclease, RNase A family, 5 | 1.61 | 0.011 |
| Arhgap30 | Rho GTPase activating protein 30 | 1.42 | 0.047 |
| Arhgap36 | Rho GTPase activating protein 36 | −1.59 | 0.024 |
| Arhgef37 | Rho guanine nucleotide exchange factor (GEF) 37 | 1.60 | 0.046 |
| Baiap3 | BAI1-associated protein 3 | −1.45 | 0.048 |
| Bcl2a1a | B-cell leukemia/lymphoma 2 related protein A1a | 1.84 | 0.030 |
| Ctbs | chitobiase, di-N-acetyl- | 1.49 | 0.048 |
| Cybb | cytochrome b-245, beta polypeptide | 2.53 | 0.010 |
| Cyp1b1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 1.56 | 0.040 |
| Cyp51 | cytochrome P450, family 51 | −1.38 | 0.047 |
| Defb7 | defensin beta 7 | 1,99 | 0.017 |
| Efemp1 | epidermal growth factor-containing fibulin-like extracellular matrix protein 1 | 1.73 | 0.047 |
| Egr1 | early growth response 1 | −1.90 | 0.003 |
| Ehbp1l1 | EH domain binding protein 1-like 1 | −1.39 | 0.038 |
| Emr1 | egf-like module containing, mucin-like, hormone receptor-like sequence 1 | 1.61 | 0.046 |
| Enc1 | ectodermal-neural cortex 1 | −1.43 | 0.017 |
| Fam70a | family with sequence similarity 70, member A | −1.46 | 0.036 |
| Fcgr3 | Cd16, Fc gamma 3R Alpha, Fc Gamma R3, Fc Gamma R3 Alpha, Fcgr3a | 1.46 | 0.030 |
| Fos | FBJ osteosarcoma oncogene | −1.75 | 0.022 |
| Gamt | guanidinoacetatemethyltransferase | −1.51 | 0.037 |
| Gcnt1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 1.60 | 0.029 |
| Glis3 | GLIS family zinc finger 3 | 1.54 | 0.045 |
| Gm16440 | predicted gene 16440 | 1.65 | 0.017 |
| Il2rg | interleukin 2 receptor, gamma chain | 1.80 | 0.047 |
| Kctd1 | potassium channel tetramerisation domain containing 1 | −1.44 | 0.048 |
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 1.74 | 0.003 |
| Naalad2 | N-acetylated alpha-linked acidic dipeptidase 2 | 1.81 | 0.002 |
| Ncf1 | neutrophil cytosolic factor 1 | 1.54 | 0.047 |
| Nell2 | NEL-like 2 (chicken) | −1.74 | 0.044 |
| Nupr1 | nuclear protein 1 | 1.42 | 0.041 |
| Pdzrn3 | PDZ domain containing ring finger 3 | −1.47 | 0.049 |
| Prkg1 | protein kinase, cGMP-dependent, type I | −1.67 | 0.030 |
| Pth2 | parathyroid hormone 2 | −1.67 | 0.030 |
| Rprm | reprimo, TP53 dependent G2 arrest mediator candidate | −1.55 | 0.031 |
| Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | 1.46 | 0.038 |
| Shisa3 | shisa homolog 3 (Xenopus laevis) | −1.86 | 0.014 |
| Tceal5 | transcription elongation factor A (SII)-like 5 | −1.51 | 0.048 |
| Tmeff2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | −1.32 | 0.048 |
| Txlnb | taxilin beta | 1.53 | 0.042 |
| Ube3a | ubiquitin protein ligase E3A | −1.86 | 0.038 |
| Zbtb26 | zinc finger and BTB domain containing 26 | −1.40 | 0.048 |
*
Comparing 18 months old to 2 months old mice, positive numbers corresponded to up-regulated genes, whereas negative numbers indicated down-regulated genes.