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. 2013 Apr 30;8(4):e62445. doi: 10.1371/journal.pone.0062445

Figure 4. Ethanol disrupts memory in wildtype flies an effect removed by the KCNQ mutation.

Figure 4

A. Flies received an overnight (∼12 hr) exposure to 10% ethanol and were tested for 2 min memory. 2-way ANOVA showed a significant effect due to genotype and ethanol (p<0.05). Post-hoc analysis showed that in KCNQ control ethanol caused a reduction (p<0.05) in memory compared to water. The reduction in memory was removed by the KCNQ mutation that had similarly low memory with or without ethanol (p>0.05). B. Ethanol content of KCNQ mutant and control (CSw- wildtype) flies exposed to 10% ethanol solution for ∼12 hr was similar (p>0.05, unpaired t-test, 20 flies per n).