Table 3. Excess cumulative incidence function post bleed by time post bleed.
| Cause of Death | Age Range | 1 mo | 1 y | 5 y | |||
| eCIF | (95% CI) | eCIF | (95% CI) | eCIF | (95% CI) | ||
| Upper GI Neoplasms | ≤50 y | 0.11 | (−0.00 to 0.22) | 0.43 | (0.22–0.64) | 0.61 | (0.33–0.89) |
| 50–59 y | 1.15 | (−0.30 to 2.59) | 3.11 | (1.53–4.68) | 3.62 | (2.02–5.22) | |
| 60–69 y | 1.76 | (−0.35 to 3.87) | 5.58 | (3.33–7.82) | 6.58 | (4.28–8.89) | |
| 70–79 y | 1.47 | (−0.28 to 3.21) | 4.76 | (2.91–6.61) | 5.65 | (3.70–7.59) | |
| ≥80 y | 1.20 | (−0.12 to 2.52) | 3.83 | (2.35–5.31) | 4.41 | (2.79–6.03) | |
| Other Neoplasms | ≤50 y | 0.51 | (0.27–0.75) | 1.00 | (0.64–1.36) | 1.29 | (0.86–1.72) |
| (Not Upper GI) | 50–59 y | 1.45 | (0.93–1.96) | 3.45 | (2.63–4.27) | 4.17 | (3.17–5.18) |
| 60–69 y | 2.39 | (1.83–2.96) | 5.65 | (4.54–6.75) | 6.64 | (5.22–8.06) | |
| 70–79 y | 1.82 | (1.39–2.25) | 4.68 | (3.70–5.65) | 5.23 | (3.87–6.59) | |
| ≥80 y | 1.95 | (1.50–2.40) | 4.82 | (3.52–6.11) | 4.38 | (2.65–6.12) | |
| Cardiovascular | ≤50 y | 0.14 | (0.02–0.26) | 0.38 | (0.17–0.60) | 0.62 | (0.32–0.92) |
| 50–59 y | 0.37 | (0.11–0.64) | 1.44 | (0.92–1.96) | 2.36 | (1.53–3.19) | |
| 60–69 y | 1.12 | (0.74–1.49) | 3.04 | (2.31–3.78) | 4.66 | (3.52–5.80) | |
| 70–79 y | 2.40 | (1.89–2.91) | 5.25 | (4.19–6.32) | 6.44 | (4.76–8.12) | |
| ≥80 y | 3.92 | (3.21–4.63) | 8.66 | (6.30–11.03) | 7.64 | (3.97–11.30) | |
| Respiratory a | ≤50 y | 0.03 | — | 0.24 | — | 0.31 | — |
| 50–59 y | 0.16 | — | 0.58 | — | 1.04 | — | |
| 60–69 y | 0.56 | — | 1.28 | — | 2.08 | — | |
| 70–79 y | 0.97 | — | 2.46 | — | 3.24 | — | |
| ≥80 y | 2.28 | — | 4.95 | — | 4.56 | — | |
| Digestive | ≤50 y | 1.01 | (0.28–1.75) | 2.28 | (1.43–3.14) | 3.04 | (2.06–4.02) |
| 50–59 y | 1.96 | (0.25–3.67) | 4.04 | (2.23–5.84) | 5.33 | (3.45–7.22) | |
| 60–69 y | 1.93 | (0.27–3.59) | 3.15 | (1.47–4.83) | 3.90 | (2.17–5.63) | |
| 70–79 y | 2.60 | (0.67–4.53) | 4.01 | (2.05–5.98) | 4.45 | (2.46–6.43) | |
| ≥80 y | 6.43 | (2.43–10.42) | 8.19 | (4.20–12.17) | 8.56 | (4.58–12.54) | |
| Other | ≤50 y | 0.26 | (0.09–0.44) | 0.95 | (0.61–1.29) | 1.65 | (1.10–2.19) |
| 50–59 y | 0.53 | (0.21–0.85) | 1.90 | (1.26–2.53) | 3.09 | (2.17–4.02) | |
| 60–69 y | 0.70 | (0.42–0.98) | 1.85 | (1.31–2.38) | 2.37 | (1.63–3.11) | |
| 70–79 y | 0.92 | (0.65–1.19) | 2.58 | (1.99–3.17) | 3.06 | (2.15–3.97) | |
| ≥80 y | 2.29 | (1.78–2.80) | 4.37 | (2.96–5.78) | 2.54 | (0.58–4.50) | |
95% CIs obtained by bootstrapping (500 iterations).
a
CIs were too unstable to be interpretable for respiratory causes of death due to small numbers.
eCIF, excess CIF; the absolute difference in the CIF between patients with non-variceal bleeding and age, sex, year, and general practice matched controls without non-variceal bleeding; GI, gastrointestinal.