Fig. 2.
egl-18::mCherry transcriptional reporter responds to activation or reduction of Wnt signaling. All worms express egl-18::mCherry. (A) Wild-type worms with 16 seam cells. The seam cells on the other side of the animal appear as blurred spots. (B) pop-1 RNAi treatment results in increased number of seam cells strongly expressing egl-18::mCherry. (C) At the restrictive temperature, wrm-1(ne1982ts) worms show fewer seam cells that are weakly expressing egl-18::mCherry (asterisks). Anterior is towards the left and ventral is downwards in all panels. Scale bars: 50 μm.