Table 3.
Systemic sclerosis (SSc) clinical correlations with microscopy findings.
| Clinical Features | TEM: Basal Lamellation | Immunohistochemistry: CD34 Area | Whole-field Digital Microscopy: Trichrome Stain |
|---|---|---|---|
| SSc duration (1st non-RP symptom) | 0.05 (0.83)* | –0.08 (0.74)* | –0.50 (0.04)* |
| mRSS | 0.34 (0.16)* | –0.04 (0.87) | –0.09 (0.71) |
| ILD | — (0.84)** | –0.45 (0.06) | 0.19 (0.43) |
| Scl-70 antibody | — (0.38)** | –0.04 (0.88) | 0.06 (0.80) |
| RNA polymerase III | — (0.66)** | –0.13 (0.60) | –0.21 (0.39) |
| Centromeric antibody | — (1.00)** | 0.02 (0.93) | 0.07 (0.76) |
| Hand edema | — (0.80)** | 0.23 (0.35) | –0.07 (0.76) |
| Foot edema | — (0.07)** | 0.05 (0.85) | –0.02 (0.92) |
TEM: transmission electron microscopy; RP: Raynaud's phenomenon; mRSS: modified Rodnan skin score; ILD: interstitial lung disease.
Spearman's Rho (p value)
Fisher's exact p value.