Table 1. Baseline Characteristics and Physiologic Measures.
| All results presented as medians (25th, 75th percentile) or N (percent). | |||
|---|---|---|---|
| Obese | Lean | p-value | |
| Baseline Characteristics | N=74 | N=67 | |
| Age (years) | 52.0(46.0,60.0) | 50.0(38.0,60.0) | 0.2391 |
| African-American | 30(40.5%) | 30(44.8%) | 0.6115 |
| Female | 52(70.3%) | 38(56.72%) | 0.0944 |
| BMI | 36.6(32.7,40.7) | 23.2(21.8,23.8) | <0.0001 |
| Lean, BMI<25 kg/m2 | 0(0.0%) | 67(100.0%) | <0.0001 |
| Obese, stage I (30-34.9kg/m2) | 28(37.8%) | 0(0.0%) | |
| Obese, stage II (35-39.9 kg/m2) | 24(32.4%) | 0(0.0%) | |
| Obese, stage III (≥40 kg/m2) | 22(29.7%) | 0(0.0%) | |
| Waist circumference (cm)* | 112.6(103.9,117.7) | 84.1(78.0,88.7) | <0.0001 |
| Taking lipid medication | 29(39.2%) | 9(13.4%) | 0.0006 |
| Taking blood pressure medication | 50(67.6%) | 16(23.9%) | <0.0001 |
| Dietary intake (% of kcal) | N=66 | N=66 | |
| Fat | 42.2(37.1,46.8) | 35.7(31.1,39.7) | <0.0001 |
| Carbohydrate | 43.4(37.6,48.7) | 50.0(41.9,55.0) | 0.0005 |
| Protein | 15.5(13.5,18.2) | 14.3(13.0,16.9) | 0.0719 |
| Physical activity (METs)** | 1431(459,3510) | 2126(1386,3816) | 0.0957 |
| Physiologic Measures*** | |||
| Body composition | |||
| Fat mass (kg) | 36.45(31.92,43.38) | 18.65(13.66,21.38) | <0.0001 |
| Lean mass (kg) | 55.09(49.60,68.43) | 45.45(41.28,58.20) | <0.0001 |
| Subcutaneous fat (area) | 37903.00(34958.00,46235.0) | 16176.00(12186.00,22042.00) | <0.0001 |
| Visceral fat (area) | 20971.00(14004.00,26325.00) | 6712.50(4068.50,9865.00) | <0.0001 |
| Resting metabolic rate | |||
| REE/LBM | 28.02(25.98,30.41) | 29.32(26.84,32.06) | 0.027 |
| RER(RQ) | 0.85(0.79,0.90) | 0.81(0.78,0.84) | 0.0038 |
| Insulin resistance | |||
| HOMA | 5.73(3.88,8.29) | 2.51(2.01,3.32) | <0.0001 |
| Si | 2.12(1.27,2.99) | 4.44(3.66,6.30) | <0.0001 |
| AIRg | 599.00(329.00,924.00) | 398.00(223.00,569.00) | 0.0491 |
*
N for mea surement of waist circumference = 68 for obese and 62 for lean.
**
N for measurement of physical activity = 47 for obese and 59 for lean.
***
N varies due to variations in completion of data collection.
N for fat and lean mass = 48 for obese and 64 for lean.
N for subcutaneous fat = 41 and 60 and for visceral fat = 47 and 60 for obese and lean, respectively.
N for REE/LBM = 45 obese and 62 for lean; N for RER = 53 and 62 for obese and lean.
N for HOMA = 74 for obese and 67 for lean.
N for Si = 26 for obese and 25 for lean and AIRg = 26 for both obese and lean, respectively.