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Gpat1−/− mice on the C3H strain background had decreased Gpat1 expression and activity in liver. (A) Gpat1 mRNA abundance in C57Bl/6 and C3H control livers. (B) Gpat2, Gpat3, and Gpat4 mRNA abundance in control and Gpat1−/− livers on the C3H background. (C) GPAT-specific activity in control and Gpat1−/− livers on the C3H background. Data represent the average ± SEM; *p ≤ .05, **p ≤ .01, ***p ≤ .001, between genotypes.
