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Representative photomicrographs of lesions in C3H livers. (A) Hematoxylin and eosin-stained basophilic focus of altered hepatocytes; (B) clear cell focus of altered hepatocytes; (C) low magnification of an hepatocellular adenoma; (D) high magnification of an hepatocellular carcinoma characterized by pleomorphic hepatocytes forming irregular trabeculae that are often three cells or greater in width.
