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. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: Arch Gen Psychiatry. 2012 Oct;69(10):1044–1053. doi: 10.1001/archgenpsychiatry.2011.2094

Table 3.

Change in ¹⁸F-Dopa Uptake (Ki) and Turnover (EDT) During Interferon Alfa Administration

Region	¹⁸F-Dopa Turnover, Mean (SEM)
	Cluster Ki (k rate 1/min)				EDT
	Baseline (Visit 1)	Treatment (Visit 2)	Delta	P Value^a	Baseline (Visit 1)	Treatment (Visit 2)	Delta	P Value^a
Caudate
Left	0.0102	0.0111	0.00097 (0.000282)	<.01	0.594	0.550	−0.0436 (0.0105)	<.01
Right	0.0096	0.0105	0.00086 (0.000307)	<.05	0.623	0.587	−0.0358 (0.0116)	<.05
Bilateral	0.0099	0.0108	0.00092 (0.000290)	<.01	0.608	0.567	−0.0401 (0.0108)	<.01
Putamen
Left	0.0122	0.0134	0.00118 (0.000333)	<.005	0.481	0.445	−0.0367 (0.00707)	<.005
Right	0.0135	0.0149	0.00150 (0.000402)	<.005	0.451	0.419	−0.0326 (0.00821)	<.005
Bilateral	0.0128	0.0141	0.00133 (0.000360)	<.005	0.466	0.432	−0.0345 (0.00744)	<.005

Abbreviations: EDT, effective dopamine turnover; ¹⁸F-dopa, fluorodopa F 18.

^a

P values were obtained by paired t tests.