Skip to main content
. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Mar 15;32(5):1124–1131. doi: 10.1161/ATVBAHA.111.239558

Figure 1. Insulin receptor expression and tyrosine phosphorylation in liver.

Figure 1

A, Representative Western blots based on lysate of liver from control (c) and haploinsufficient (Δ) mice (Insr flox/ flox Apoe−/− and Insr flox/Δ Apoe−/−, respectively). M, molecular weight marker. B, Insulin (50 mU/g) or insulin diluent was injected in the vena cava during pentobarbital anesthesia. After 5 minutes, organs were isolated and flash frozen. Representative Western blots based on phospho-tyrosine immunoprecipitates from liver lysate using tissue from control (c) and haploinsufficient (Δ) mice. C, Average values from 6 control and 5 haploinsufficient animals (left) and from 6 control and 6 haploinsufficient animals (right).