Table 2.
Comparison of Patients with Different Levels of Interstitial Inflammation
| Demographic/Clinical Feature/Biomarker Level | No-Mild Inflammation | Moderate-Severe Inflammation |
|---|---|---|
| Caucasian (%) | 25 (53) | 4 (24) |
| African American (%) | 16 (34) | 11 (64)1 |
| Other (%) | 6 (13) | 2 (12)1 |
| Age | 30±1.1 | 32±2.1 |
| Mean SCr2 (mg/dl) | 1.09±0.10 | 2.61±0.37 |
| Mean uPCR3 | 2.80±0.42 | 5.33±1.234 |
| Class II (%) | 6 (13%) | 0 |
| Class III, III+V (%) | 11 (23%) | 4 (23.5%) |
| Class IV, IV+V (%) | 25 (53%) | 12 (70.5%) |
| Class V (%) | 5 (11%) | 1 (6%) |
| uMCP-1 (ng/mg Cr) | 1.22±0.15 | 5.21±1.185 |
| uHepcidin (ng/mg Cr) | 235±55 | 658±2296 |
| uLFABP (ng/mg Cr) | 71±10 | 152±317 |
1
African American plus other races/ethnicities were significantly over-represented in the moderate-severe interstitial inflammation group (P=0.048, Fisher’s exact test)
1
Serum creatinine ±SEM
2
Urine protein creatinine ratio
4
P<0.0001 vs no-mild inflammation (Mann-Whitney test)
5
Biomarker Levels are mean±SEM; P<0.0001 vs no-mild inflammation (Mann-Whitney test)
6
P<0.003 vs no-mild inflammation (Mann-Whitney test)
7
P<0.002 vs no-mild inflammation (Mann-Whitney test)