C3-day concentrations of ten 2-AMT compounds and Compd B in brain (top) and plasma (bottom) following 3-day dosing in liquid diet. Doses were 40, 80, 130, and 210 mg/kg/day for the 2-AMTcompounds, and 25, 50, 100, and 150 mg/kg/day for Compd B. Mean values (n=3) are plotted; mean ± SD values are shown in the Supplementary Material Table. In several instances, concentrations at low doses were below the lower limit of quantification by LC/MS/MS; these brain concentrations appear as missing values.