Table 2.
Effects of HPN on blood glucose level in db/db mice.
| Group | Dose (mg/kg) | Plasma glucose (mmol/L) a | |||
|---|---|---|---|---|---|
| Baseline | 1 week | 4 weeks | 8 weeks | ||
| Control | 6.0 ± 0.6 | 6.0 ± 0.4 | 6.1 ± 0.3 | 5.8 ± 0.4 | |
| Model | 18.9 ± 4.5 ** | 20.0 ± 3.6 ** | 20.2 ± 4.6 ** | 18.9 ± 4.1 ** | |
| HPN | 40 | 19.8 ± 5.0 | 15.1 ± 3.6 ## | 14.7 ± 3.7 ## | 15.8 ± 2.4 # |
| 20 | 18.6 ± 4.5 | 16.6 ± 3.4 # | 15.4 ± 4.7 # | 15.5 ± 3.3 # | |
| 10 | 19.4 ± 4.9 | 16.0 ± 3.7 # | 17.5 ± 3.9 | 16.5 ± 3.5 | |
| Rosiglitazone | 20 | 18.7 ± 3.8 | 15.5 ± 4.0 # | 15.6 ± 3.1 # | 13.9 ± 2.9 ## |
a Data are expressed as means ± SD, n = 10; # P < 0.05, ## P < 0.01 when compared to the model group; ** P < 0.01 when compared to the control group.