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. 2013 Jan 30;11(2):350–362. doi: 10.3390/md11020350

Table 3.

Effects of HPN on serum lipid in db/db mice.

Group Dose (mg/kg) Triglycerides (mmol/L) a Total cholesterol (mmol/L) a
Baseline 4 weeks 8 weeks Baseline 4 weeks 8 weeks
Control 1.19 ± 0.25 1.30 ± 0.26 1.19 ± 0.24 3.01 ± 0.83 3.32 ± 0.80 2.99 ± 0.72
Model 1.47 ± 0.30 * 1.69 ± 0.39 * 1.74 ± 0.40 ** 4.20 ± 1.17 * 7.22 ± 2.91 ** 7.18 ± 2.18 **
HPN 40 1.36 ± 0.35 1.32 ± 0.21 # 1.32 ± 0.34 # 3.89 ± 0.93 4.67 ± 1.55 # 5.01 ± 1.64 #
20 1.44 ± 0.42 1.32 ± 0.27 # 1.36 ± 0.31 # 3.86 ± 1.42 5.01 ± 1.45 5.12 ± 2.31
10 1.44 ± 0.28 1.45 ± 0.30 1.47 ± 0.32 4.72 ± 0.91 5.54 ± 1.59 5.79 ± 1.69
Rosiglitazone 20 1.46 ± 0.23 1.33 ± 0.27 # 1.36 ± 0.23 # 4.19 ± 1.04 4.67 ± 1.42 # 4.44 ± 1.60 ##

a Data are expressed as means ± SD, n = 10; # P < 0.05, ## P < 0.01 when compared to the model group; ** P < 0.01 when compared to the control group.